PhanArt To Return To NYC For Special Pre-Phish Concert With Space Carnival

first_imgWith Phish set to hit New York City for three straight weeks for this summer’s Baker’s Dozen run at Madison Square Garden, the number of pre-and-post show activities keeps growing exponentially. One pre-party of note will feature the return of beloved jam scene staple PhanArt to American Beauty.PhanArt will team up with Live For Live Music for another musical edition in New York City, this time featuring up-and-comers Space Carnival, who will perform two sets on the first floor of the venue. PhanArt will bring several artists–many of whom have never shown their art at a PhanArt event before–to the venue’s second floor for a combined art and music experience. Just like the successful PhanArt show at American Beauty during last year’s New Years Eve run, the music from downstairs will be playing upstairs, so fans can enjoy the music and art simultaneously. The show will run from 3:00 pm to 7:00 pm, and will provide Phish fans with the perfect pre-show opportunity to enjoy some drinks, free pizza, good live music, and unique, fan-made art that can only be experienced at PhanArt.last_img read more

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The Marcus King Band Announce New EP, ‘Due North,’ Due Out Next Month

first_imgThe Marcus King Band has been on a skyward path since the release of their self-titled sophomore album in 2016, touring relentlessly and building a fervent global following along the way. Propelled by prodigious guitarist/vocalist/bandleader Marcus King, the band has gone from playing small rooms and midday festival sets to headlining national tours and even hosting their own two-day Marcus King Band Family Reunion festival in North Carolina next weekend.Yesterday, the band announced that they will release a brand new EP, Due North, on October 27th. The band’s announcement of the 4-track collection refers to the EP as “a love note from the band of words we didn’t get to say. Songs that are a big part of our live repertoire that we would like to share with everyone.” In addition to three studio tracks (“What’s Right,” “This Ol’ Cowboy,” and “Slip Back”), the Due North EP will feature an exclusive live recording of the band’s “Sharry Barry” medley from a performance in Chicago last winter, giving fans a taste of the band’s thrilling live shows.Watch The Marcus King Band perform “What’s Right” live at Callahan’s earlier this year below, via YouTube user bluzdudemi:For more information on the Marcus King Band’s upcoming projects and performances, head to their website.The Marcus King Band Due North Tracklist:1. What’s Right2. This Ol’ Cowboy3. Slip Back4. Sharry Barry/Sliced Milk/25 Or 6 To 4/I’ll Stay/Gloomy Sunday (Live)[Cover Photo via Emily Butler]last_img read more

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Harvard carrying Dell on campus, online

first_imgAt Harvard’s Technology Products and Services, personal purchasers can now buy a selection of Dell notebooks, desktops, and displays on campus. Visit the Campus Computer Store located at the Science Center or purchase online at http://www.computers.harvard.edu. Click “Shop for Yourself,” and log in with your Harvard University ID (HUID) and PIN.Departments that wish to purchase Dell products will continue to buy directly from Dell through the Harvard Crimson Online Marketplace (HCOM). To access the link to the HCOM portal, visit http://www.computers.harvard.edu, click “Shop for a Harvard Department,” and log in with your HUID and PIN.last_img

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Antibody halts cancer-related wasting condition

first_imgNew research from scientists at Dana-Farber Cancer Institute, a Harvard affiliate, raises the prospect of more effective treatments for cachexia, a profound wasting of fat and muscle that occurs in about half of all cancer patients, raising their risk of death.Many strategies have been tried to reverse the condition, which can cause such frailty that patients can’t endure potentially life-saving treatments, but none have had great success.In the July 13 advanced online edition of Nature, scientists led by Bruce Spiegelman, the Stanley J. Korsmeyer Professor of Cell Biology and Medicine at Harvard Medical School, reported that symptoms of cachexia in mice with lung tumors improved or were prevented when the mice were given an antibody that blocked the effects of a protein, PTHrP, secreted by the tumor cells. PTHrP, which stands for parathyroid hormone-related protein, is known to be released from many types of cancer cells.The scientists said their findings were the first to explain in detail how PTHrP from tumors switches on a thermogenic (heat-producing) process in fatty tissues, resulting in unhealthy weight loss. They found that the tumor-derived protein stimulated “beige” or brown fat cells mixed with stored white fat in the body. The stimulation caused white fat to “brown” — that is, generate heat and cause weight loss even when the animals were at rest.The researchers carried out two experiments using mice that developed lung tumors and cachexia. In one, they administered a polyclonal antibody that specifically neutralizes PTHrP and found that it almost completely prevented the wasting, while untreated animals became mildly cachexic. In the second, the antibody treatment prevented the loss of muscle mass and improved muscle function, while control animals developed severe muscle wasting.“You would have expected, based on our first experiments in cell culture, that blocking PTHrP in the mice would reduce browning of the fat,” said Spiegelman. “But we were surprised that it also affected the loss of muscle mass, and improved health.”The research suggested that PTHrP alone doesn’t directly cause muscle wasting, yet blocking the protein’s activity prevents it. Thus, the role of PTHrP “is definitely not the whole answer” to the riddle of cachexia, noted Spiegelman, but it may be a necessary part, with other factors also involved.A collaborator on the study, Vickie E. Baracos at the University of Alberta in Edmonton, Canada, provided blood from 47 patients with lung or colon cancer who were cachexic. First author Serkan Kir from the Spiegelman lab, a Robert Black Fellow of the Damon Runyon Cancer Research Foundation, found increased levels of PTHrP in 17 of the patients; these had significantly lower lean body mass and produced more heat energy at rest than the other patients in the group.It may turn out that the PTHrP mechanism is responsible for cachexia in a subset of cancer patients, but not all, Spiegelman suggested. Before trying the anti-PTHrP antibody in human patients, he said, “clinicians would probably first want to find out if the protein is elevated in certain cancers, and determine which patients would be good candidates for a clinical trial.”Barrett Rollins, Dana-Farber’s chief scientific officer, commented that the report from Spiegelman and his colleagues “provides a new road map for developing a rational, mechanistically based treatment for this incredibly debilitating condition that occurs in such a large number of our patients. Until now we’ve had no truly effective way to reverse this horrible complication.”Patients with upper gastrointestinal and pancreatic cancers are the likeliest to develop cachexia, which affects about 80 percent of terminal cancer patients. Currently these patients are given appetite stimulants and nutrient supplements, along with medications to counteract some of the molecular pathways believed to underlie the wasting process, but this treatment has had only limited success.The research was supported by National Institutes of Health.last_img read more

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Diversity Council trains student senators

first_imgThe student Senate meeting Wednesday night focused on diversity training for the senators. The training consisted of four different presentations given by students on the Diversity Council, which represent different cultural and religious backgrounds and concluded with a presentation by student body vice president Matt Devine.The University needs a balance of cultures on campus, Daphne Reynolds, the diversity council representative for the Native American Student Association of Notre Dame (NASAND), said.“Being mixed race in a family setting means learning how to be balanced,” Reynolds said. “You can’t choose one ethnicity over the other because this would be denying the importance of the other culture and demeaning your child in a way. Diversity is a big part of ensuring that we don’t forget who we are.”Sophomore Muslim Student Association Representative Khaoula Morchid followed Reynolds with a presentation about religious diversity on campus and her experience as an international student.“One of the highlights of my time at Notre Dame has been the opportunity to look at faith from a different perspective and not from a specific religion,” Morchid said. “It’s so enlightening to hear stories about countries and cultures that I wouldn’t know much about otherwise. Ask questions and explore rather than assume what someone has lived.”Senior Veronica Guerrero, the First Class Steppers Diversity Council Representative, said students should get involved in different activities on campus that are not associated with their ethnicity.“If your friends invite you to activities for ethnicities that you aren’t necessarily a part of, it’s because they want you to go, not because they want you to feel awkward,” Guerroro said. “Just because you’re not part of the ethnicity or religion doesn’t mean you can’t go to their events, the group wants you there.”After sharing the story of his personal identity, Devine said a strong sense of self should encourage acceptance of others.“Even though we comprise ourselves of different categories and we come from different dorms, quads, states, religions, that it is something that is specific to you,” Devine said. “Hopefully a self-awareness of our own identities will lead to a different type of awareness of other people and where they come from.”Devine said he sees an occasional disparity between how his peers identify themselves and how they tend to stereotype others.“In a way we’re all minorities because we only know our own story and a little bit of other people’s,” Devine said.Tags: diversity council, Senate, senate group, Student governmentlast_img read more

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Coal-fired electric generation in India expected to fall for the first time in 14 years

first_imgCoal-fired electric generation in India expected to fall for the first time in 14 years FacebookTwitterLinkedInEmailPrint分享Bloomberg:Coal’s use for power in India is set to shrink for the first time in at least 14 years as demand slows and cheaper and cleaner renewable sources of electricity erode the fossil fuel’s share.Coal generation fell for a fourth month in November, the longest such streak in government data going back to 2005. That echoes a decline in consumption because of slowing industrial activity and prolonged rains that pushed up production from hydroelectric dams while curbing electricity demand for air conditioning and irrigation.When demand is down, utilities end up reducing offtake from costlier coal plants, and buy more from other sources such as hydro, renewables and nuclear, said Sambitosh Mohapatra, partner for power and utilities at PricewaterhouseCoopers India.Power generation from coal, the most polluting fossil fuel, slumped 11% from a year earlier in November. Output in the year to November fell 2.4%, the first ever drop for the 11-month period.India has a coal-fired generation capacity of almost 198 gigawatts, which accounts for about 54% of its installed generation capacity. That share has reduced over the past years and is set to come down further as the country adds more clean power to deal with air pollution and meet its climate goals. India’s coal fleet used barely 51.4% of its capacity in November, compared with 60.5% a year earlier, Central Electricity Authority data showed.[Rajesh Kumar Singh]More: India’s coal power usage set to shrink for first time in 14 yearslast_img read more

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Start your engines…online!

first_img 9SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr,Frank Rinaudo Frank Rinaudo is Senior Vice President of GrooveCar Inc. and CU Xpress Lease, he has been responsible for the direction of the company since 2001 following an 18-year career at … Web: www.groovecarinc.com Details Auto buying has changed dramatically in the last several decades. The purchase of a car no longer starts when a customer walks through the door of a dealership. So it is important for credit unions to engage potential members at the beginning of the process. Shoppers for new and pre-owned vehicles start exploring makes and models on their mobile devices anywhere from one to four months before ever stepping foot on a car lot. They are educated about what they like and they are adamant about what they don’t want. If you think just young hipsters, you are partially right; the active older baby-boomer is also tech savvy. So the car choices in the end may be generations apart, but the methodology is the same.Because the initial leg-work is being done online it is important to meet the member where they live, ONLINE! Trips to the dealership to kick the tires are now done with virtual test drives. Payment calculators prepare the consumer for monthly financial expectations. When the consumer arrives at the dealership they are armed and ready to go. In the past, consumers would typically visit up to five dealerships, now a decade later, the average amount of dealerships visited is 1.6. The Internet is a chief conduit in pushing sales, which cannot be ignored.Researching cars online is done by 95 percent of shoppers. Consumers avoid in-person contact to cull information, instead peruse data and reviews about their next purchase on auto buying resource sites. Partnerships with both dealerships and financing providers will help to usher the process along as the average buyer, once the decision has been made, will move quickly to make it happen. Industry studies have found both new and pre-owned car shoppers will look to complete their car purchase in less than 16 hours. The quick and efficient car shopping experience has arrived.With 65 million vehicles being purchased by millennials in the next 5 years, it is important to understand what this group is looking for in a car. This generation wants powerful acceleration, responsive handling, technology and a streamlined buying process. Boomers and seniors are credited with being one in four mobile shoppers in the U.S. This group is gravitating towards technology such as roadside assistance and crash avoidance. Larger cars with connectivity features are especially attractive to the male boomer. Car buying resource sites will help to achieve these goals, bring members in for a loan or a lease that fits their budget and keep a customer returning to dealerships for servicing.last_img read more

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NCUA, regulators issue alternative appraiser options

first_imgNCUA and other federal regulators issued an advisory Wednesday highlighting 2 appraiser options to help insured depository institutions facilitate timely consideration of loan applications. During the review process mandated by the Economic Growth and Regulatory Paperwork Act, financial industry representatives raised issues attributed to limited availability of state-certified and licensed appraisers.The Financial Institutions Reform, Recovery, and Enforcement Act of 1989 (FIRREA) requires appraisals for federally related transactions to be performed by individuals who meet certification licensing requirements.According to federal regulators, alternatives that may help in areas facing a shortage of appraisers include:Temporary practice permits, which allow appraisers credentialed in one state to provide services on a temporary basis in another state experiencing a shortage of appraisers, subject to state law. The advisory also discusses reciprocity, in which one state allows appraisers that are certified or licensed in another state to obtain certification or licensing without having to meet all of the state’s certification or licensing standards; or 9SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr continue reading »last_img read more

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Move the mortgage process forward with digital validation

first_img 24SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr In an era when writing checks at the grocery store is an anomaly and having cash available is something people have to plan ahead for, many borrowers are jumping at the chance for a more digital mortgage process. When Fannie Mae rolled out Day 1 Certainty™ just over a year ago, it brought with it an industry-changing standard for a more efficient and certain loan origination process, plus freedom from paper-based processes with digital validation of income, assets, and employment.A couple of decades ago, applying for a mortgage meant gathering up paper paystubs and bank statements and delivering them to the lender by hand. Even today, most borrowers are still scanning hard copies or collecting electronic documents and emailing them to their loan officers or uploading them to web portals.The Desktop Underwriter® (DU®) validation service is making all of that obsolete for many loan applications. Instead, borrowers can consent to digital validation, avoiding the task of amassing either electronic or paper documents, and speeding up the approval process. continue reading »last_img read more

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Grand Slam of Darts 2020: Gerwyn Price, Jonny Clayton in same group after draw | Darts News

first_img Live Grand Slam of Darts November 16, 2020, 1:00pmLive on Gerwyn Price landed his first major title with victory at the Grand Slam of Darts two years ago – he will start his bid to win the title for a third year in a row on Monday World Darts ChampionshipTBC Gerwyn Price will face his World Cup-winning team-mate Jonny Clayton in Group G as he kicks off his bid for a third successive Grand Slam of Darts title.Joining the Welsh pairing in the group are Ryan Joyce and women’s BDO world champion Mikuru Suzuki, who Price lost to on his way to claiming his second Grand Slam crown last year.The Iceman is aiming to become just the third person to lift the prestigious Eric Bristow Trophy for a third successive year – a win in Coventry, where he claimed the World Grand Prix just a few weeks ago, would see him join Michael van Gerwen and Phil Taylor. – Advertisement – World no 1 Michael van Gerwen to face Joe Cullen, Gabriel Clemens and Adam Hunt as he chases first TV title since March – coverage of the Grand Slam of Darts begins on Monday with a bumper double session of action from 1pm on Sky Sports Arena Last Updated: 14/11/20 11:57pm Gerwyn Price landed his first major title with victory at the Grand Slam of Darts two years ago - he will start his bid to win the title for a third year in a row on Monday
Gerwyn Price landed his first major title with victory at the Grand Slam of Darts two years ago - he will start his bid to win the title for a third year in a row on Monday

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